Research

Examination of the TrkB receptor signalling pathway throughout the retina of glaucoma patients versus age-matched controls.

This project will improve our understanding of BDNF signalling in human retinal tissue.

Genetics of Advanced Glaucoma: Towards Predicting and Preventing Blindness

Identifying the best treatment option for patients who present with advanced glaucoma.

Targeting NAD+ for retinal ganglion cell protection in experimental glaucoma

Understanding the genetic basis for steroid-induced eye pressure to develop personalised medicine

The aim is to develop a genetic test that will predict how a patient will respond to steroids, which are widely used to treat a range of eye conditions.

Promoting RGC survival and optic nerve regeneration by enhancing the axon transport of growth and survival receptors

Regeneration of the optic nerves may be able to restore vision to those blinded by optic nerve disease and eventually make eye transplants possible.

Lifestyle determinants of intra-ocular pressure and glaucoma

Investigating the effect of a variety of lifestyle factors on eye pressure and the subsequent development of primary open angle glaucoma.

Investigating how brain-derived neurotrophic factor (BDNF) could prevent cell death in glaucoma

miRNA-mediated therapy for the treatment of glaucoma

Investigating the role of micro RNA - thought to be an integral part of the disease mechanism in glaucoma - and explore its therapeutic potential for the condition through pre-clinical testing.

Identifying measurements to predict childhood secondary glaucoma risk

ARGO-1: Study of Anterior segment imaging based Risk stratification of childhood secondary Glaucoma.