Research
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Investigating the unexpected role of transport motors inside light-detector cells
A new line of research that could lead to developing treatment for inherited retinal disorders
CompletedOctober 2016 - March 2020 -
How do faults in the RPGR gene cause X-linked retinitis pigmentosa?
Laying the groundwork for developing a cure for severe inherited blindness using gene editing technology
CompletedJanuary 2017 - April 2018 -
Cell-cell junctions in retinal disease: The role of ARHGEF18/p114RhoGEF
Researchers aim to identify the molecular mechanisms by which defective p114RhoGEF leads to malfunctioning of cell-cell junctions in retinal pigment epithelial cells and photoreceptors, and how such defects lead to degeneration of these cell types.
CompletedOctober 2018 - June 2022 -
Genotype-phenotype study of CRB1-retinopathy
To improve understanding of the natural history (or progression) of inherited retinopathies caused by faults in the CRB1 gene.
ActiveSeptember 2022 - January 2026 -
Identifying novel therapies for inherited eye disease
Investigating photoreceptor death which will act as a basis to identify novel therapies for inherited eye disease.
ActiveMay 2022 - May 2025