Research

Promoting RGC survival and optic nerve regeneration by enhancing the axon transport of growth and survival receptors

Regeneration of the optic nerves may be able to restore vision to those blinded by optic nerve disease and eventually make eye transplants possible.

Lifestyle determinants of intra-ocular pressure and glaucoma

Investigating the effect of a variety of lifestyle factors on eye pressure and the subsequent development of primary open angle glaucoma.

Mechanisms of cell death in choroideremia

Investigating how brain-derived neurotrophic factor (BDNF) could prevent cell death in glaucoma

Further investigation into intra-ocular fluid as a liquid biopsy in retinoblastoma

Investigating adaptive and innate immune cell interactions to better understand multi-morbidities affecting the eye and joints.

Making a macular patch from 3D retinal organoids

Generating 'macular patches' from human stem cells, which could be used to help repair damage to the macula and to improve understanding.

Creating a model to investigate corneal thinning in keratoconus

Investigating genetic variants leading to AMD

Researchers are looking to determine whether this system can be used to successfully identify variant pathogenicity in AMD.